Create a case

Learn how to create a secondary case in Nostos Secondary app

After the files have been made available to Nostos AWS cloud storage, a separate step to launch the cases is still needed to connect the input files to all necessary information about the case.

Launching of cases currently happens in the secondary analysis user interface by selecting "Create a new case":

A case launch form is opened asking you to detail all the necessary information: 

1. Case ID.
2. Reference genome (hg19/hg38).
3. Sample type (WGS, WES, panel)
4. BED file of sequencing target (required if sample type WES or panel for QC and definition of CNV cohort).
5. FASTQ files from proband: R1 & R2.
   For trios: upload fastq files for mother and father.
6. HPOs (optional, but highly recommended).
7. Biological sex.
8. Date of birth (optional).
9. (if trio) Affectedness status for parents.